Remdesivir for Injection is a broad-spectrum antiviral drug that gained prominence during the COVID-19 pandemic. It is used for the management of severe COVID-19 cases in hospitalized patients requiring supplemental oxygen.

Mechanism of Action:

Remdesivir is a nucleotide analog that interferes with the viral RNA-dependent RNA polymerase, thereby inhibiting viral replication.

Indications:

• Treatment of COVID-19 in adults and pediatric patients (as per health authority guidelines).

• Typically prescribed for patients with low oxygen saturation or severe respiratory symptoms.

Dosage & Administration:

• Administered intravenously (IV infusion) under strict hospital settings.

• Standard regimen: a loading dose on day 1, followed by a daily maintenance dose for 5–10 days (as per doctor’s advice).

Precautions:

• Should only be administered in healthcare facilities.

• Not a self-medication drug.

• Use with caution in patients with kidney or liver impairment.

• Monitor liver function before and during treatment.

Possible Side Effects:

• Nausea, headache, dizziness

• Liver enzyme elevation

• Allergic reactions (rare but possible)

• Infusion-related reactions such as low blood pressure, sweating, or shivering